Placental opioid-enhancing factor (POEF): Generalizability of effects
نویسندگان
چکیده
منابع مشابه
Participation of Placental Opioid-Enhancing Factor in Opioid-Modulated Events at Parturition
Endogenous opioids play a significant role in mammalian parturition as well as in the behaviors associated with delivery itself and toward the emerging young. Distention of the uterus, and distention and mechanical stimulation of the vaginal/cervical area are critical stimuli in the positive feedback loop associated with expulsion of the fetus, and in the onset of maternal behavior upon emergen...
متن کاملParticipation of Placental Opioid-Enhancing Factor in Opioid-Modulated Events at Parturition
Endogenous opioids play a significant role in mammalian parturition as well as in the behaviors associated with delivery itself and toward the emerging young. Distention of the uterus, and distention and mechanical stimulation of the vaginal/cervical area are critical stimuli in the positive feedback loop associated with expulsion of the fetus, and in the onset of maternal behavior upon emergen...
متن کاملEnhancement of opioid-mediated analgesia: a solution to the enigma of placentophagia.
Two major consequences of placentophagia, the ingestion of afterbirth materials that occurs usually during mammalian parturition, have been uncovered in the past several years. The first is that increased contact, associated with ingesting placenta and amniotic fluid from the surface of the young, causes an accelerated onset of maternal behavior toward those young. The second, which probably ha...
متن کاملIngested bovine amniotic fluid enhances morphine antinociception in rats.
Ingestion by rats of rat placenta or amniotic fluid enhances opioid-mediated, or partly opioid-mediated, antinociception produced by morphine injection, vaginal or cervical stimulation, late pregnancy, and foot shock. This phenomenon is believed to be produced by a placental opioid-enhancing factor (POEF). Ingestion by rats of human or dolphin placenta has also been shown to enhance opioid anti...
متن کاملPlacenta ingestion by rats enhances y- and n-opioid antinociception, but suppresses A-opioid antinociception
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (A, y, n) in the antinociception-modulating effects of Placental Opioid-Enhancing Factor (POEF—presumably the active substance). Antinociception was measured on a 52 jC hotplate in adult, femal...
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ژورنال
عنوان ژورنال: Physiology & Behavior
سال: 1991
ISSN: 0031-9384
DOI: 10.1016/0031-9384(91)90417-m